Isaiah is the smallest, and perhaps the most cowardly of all the mice at the "horrible place," a research laboratory. It is amazing, therefore, that when 97 genetically altered mice try to escape, Isaiah is the only one who is not caught. Despite his bright blue color, he is accepted into a nearby mischief, or mouse family group, and discovers that his scientifically augmented abilities come in handy in the outside world. He soon finds that he has become a leader among mice, but what he really wants is to find a way to free his family from the lab. In the end it is not his agility, his intelligence, or even his ability to speak with humans, but his ability to look past differences with an open heart that is the key to his success.
This book was about what you would expect form Patterson/Grabenstein. There is a lot that would appeal to children, but it seemed a little heavy handed and melodramatic to me. Part of that impression might be because of the reader in the audiobook I listened to. His inflection was a little over-the-top. Because I listened to the book instead of reading it I didn't see any of the illustrations, but the story worked fine without them. This is a good book for kids who are transitioning from intermediate to longer fiction who like animal stories and haven't yet developed a sophisticated taste in literature.